Image guided general surgery and intervention

Our group focuses on research on the results of new minimally invasive surgical techniques in addition to development of new procedures.

Kontaktinformasjon

Gruppeleder: Section Manager Bjørn Edwin, Professor, MD

Mobil: +4793008635, Office: +4723070100

e-post: bjoedw@ous-hf.no 

Bjørn Edwin.jpg

Besøksadresse/Postadresse:
The intervention Centre, Rikshospitalet, Oslo University Hospital (OUS), 
Sognsvannsveien 20, 0027 Oslo

Beskrivelse av forskningsprofil

Minimally invasive surgery is evolving rapidly, and the need for systematic development and evaluation of these methods is great. Our group focuses on research on the results of new minimally invasive surgical techniques in addition to development of new procedures. Most of the research is conducted in the field of HPB-surgery (diseases in liver, bile ducts and pancreas) and adrenal surgery.

Gruppens medlemmer

Hovedmedlemmer

Mushegh Sahakyan, PhD student, 

Stig Ronny Kristiansen, IT-researcher, 

Karl Øyri, PhD, Researcher,

Dejan Ignatovic MD, professor, 

Airazat Kazaryan MD ,PhD , 

Åsmund Avdem Fretland, PhD-student,

Leonid Barkhatov, PhD-student, 

Sven Petter Haugvik, MD, PhD, 

Davit Aghayan, PhD-student,

Vegard Dagenborg, PhD student, 

Egidijus Pelanis, PhD student.

Assosierte medlemmer

Anne Waage , MD, PhD, 

Knut Jørgen Labori MD, PhD, 

B.A. Bjørnbeth , MD, PhD, 

 Trond Buanes, MD, professor, 

Bård Røsok, MD, PhD, 

Kjersti Flatmark, MD, professor.

Prosjekter

  • Active externally funded projects
  • HSØ: Economic evaluation of laparoscopic versus open liver resection for colorectal metastasis. A cost utility analysis alongside the Oslo CoMet prospective RCT.
  • Prospective randomized study of laparoscopic versus open liver resection for liver metastasis (final phase).
  • Laparoscopic liver resection: 3 randomized trials.
  • Kreftforeningen: HIFU: High Intensity Focus Ultrasound Ablation of the Liver under 3T MR Guidance (Refinement experimental study). (final phase)
  • European Association of Endoscopic Surgery: Pancreas consensus project:
  • Kvote programmet Pancreatic research
  • EU project HiPerNav Livernavigation

Samarbeid

  • Nasjonalt kompetansetjeneste for ultralyd
  • og bildeveiledet behandling, Trondheim
  • Tumorbiologi, Radiumhospitalet, OUS
  • PubGen, Oslo
  • Nasjonalt kompetansetjeneste for ultralyd
  • og bildeveiledet behandling, Trondheim
  • Tumorbiologi, Radiumhospitalet, OUS
  • PubGen, Oslo
  • Prof Robert Troisi, 
  • Dept. of General and Hepato-Biliary Surgery and
  • Liver Transplantation Service
  • Ghent University Hospital Medical School – BELGIUM
  • Prof Mohammad Abu Hilal, Faculty of Medicine, Southampton University
  • Research and development lead for Surgery
  • Southampton University hospital –Great Britain
  • Dr Luca Aldrighetti Chief of Liver Unit, Department of Surgery,Scientific Institute San
  • Raffaele, University Vita-Salute San Raffaele, Milan, Italy.
  • + many other European centers (both for publications and teaching)

Utvalgte publikasjoner

  1. Can standardized pathology examination increase the lymph node yield following laparoscopic distal pancreatectomy for ductal adenocarcinoma?Sahakyan MA, Haugvik SP, Røsok BI, Kazaryan AM, Ignjatovic D, Buanes T, Labori KJ, Verbeke CS, Edwin B.HPB (Oxford). 2017 Sep 21. pii: S1365-182X(17)30943-7. doi: 10.1016/j.hpb.2017.08.038. [Epub ahead of print] PMID: 28943397
  2. Laparoscopic liver resection for metastatic melanoma.Aghayan DL, Kazaryan AM, Fretland ÅA, Sahakyan MA, Røsok BI, Bjørnbeth BA, Edwin B. Surg Endosc. 2017 Sep 15. doi: 10.1007/s00464-017-5834-0. [Epub ahead of print]PMID: 28916919
  3. Evolution of Laparoscopic Liver Surgery from Innovation to Implementation to Mastery: Perioperative and Oncologic Outcomes of 2,238 Patients from 4 European Specialized Centers. Berardi G, Van Cleven S, Fretland ÅA, Barkhatov L, Halls M, Cipriani F, Aldrighetti L, Abu Hilal M, Edwin B, Troisi RI. J Am Coll Surg. 2017 Aug 31. pii: S1072-7515(17)31768-4. doi: 10.1016/j.jamcollsurg.2017.08.006. [Epub ahead of print] PMID: 28838869
  4. Trends in indications, complications and outcomes for venous resection during pancreatoduodenectomy.Kleive D, Sahakyan MA, Berstad AE, Verbeke CS, Gladhaug IP, Edwin B, Fosby B, Line PD, Labori KJ.Br J Surg. 2017 Oct;104(11):1558-1567. doi: 10.1002/bjs.10603. Epub 2017 Aug 17. PMID: 28815556
  5. Laparoscopic distal pancreatectomy for pancreatic ductal adenocarcinoma: Long-term oncologic outcomes after standard resection. Sahakyan MA, Kim SC, Kleive D, Kazaryan AM, Song KB, Ignjatovic D, Buanes T, Røsok BI, Labori KJ, Edwin B. Surgery. 2017 Oct;162(4):802-811. doi: 10.1016/j.surg.2017.06.009. Epub 2017 Jul 27. PMID: 28756944
  6. Laparoscopic liver resections for hepatocellular carcinoma. Can we extend the surgical indication in cirrhotic patients? Cipriani F, Fantini C, Ratti F, Lauro R, Tranchart H, Halls M, Scuderi V, Barkhatov L, Edwin B, Troisi RI, Dagher I, Reggiani P, Belli G, Aldrighetti L, Abu Hilal M. Surg Endosc. 2017 Jul 17. doi: 10.1007/s00464-017-5711-x. [Epub ahead of print] PMID: 28717870
  7. Laparoscopic Versus Open Resection for Colorectal Liver Metastases: The OSLO-COMET Randomized Controlled Trial. Fretland ÅA, Dagenborg VJ, Bjørnelv GMW, Kazaryan AM, Kristiansen R, Fagerland MW, Hausken J, Tønnessen TI, Abildgaard A, Barkhatov L, Yaqub S, Røsok BI, Bjørnbeth BA, Andersen MH, Flatmark K, Aas E, Edwin B; Oslo-CoMet study group. Ann Surg. 2017 Jun 27. doi: 10.1097/SLA.0000000000002353. [Epub ahead of print] PMID: 28657937
  8. Conversion for Unfavorable Intraoperative Events Results in Significantly Worst Outcomes During Laparoscopic Liver Resection: Lessons Learned From a Multicenter Review of 2861 Cases. Halls MC, Cipriani F, Berardi G, Barkhatov L, Lainas P, Alzoubi M, D'Hondt M, Rotellar F, Dagher I, Aldrighetti L, Troisi RI, Edwin B, Hilal MA. Ann Surg. 2017 Jun 2. doi: 10.1097/SLA.0000000000002332. [Epub ahead of print] PMID: 28582270
  9. RAS Mutation Clinical Risk Score to Predict Survival After Resection of Colorectal Liver Metastases. Brudvik KW, Jones RP, Giuliante F, Shindoh J, Passot G, Chung MH, Song J, Li L, Dagenborg VJ, Fretland ÅA, Røsok B, De Rose AM, Ardito F, Edwin B, Panettieri E, Larocca LM, Yamashita S, Conrad C, Aloia TA, Poston GJ, Bjørnbeth BA, Vauthey JN. Ann Surg. 2017 May 25. doi: 10.1097/SLA.0000000000002319. [Epub ahead of print] PMID: 28549012
  10. A novel method for planning liver resections using deformable Bézier surfaces and distance maps. Palomar R, Cheikh FA, Edwin B, Fretland Å, Beghdadi A, Elle OJ. Comput Methods Programs Biomed. 2017 Jun;144:135-145. doi: 10.1016/j.cmpb.2017.03.019. Epub 2017 Mar 27. PMID: 28494998 Free Article
  11. Preoperative liquid gastric emptying rate does not predict outcome after fundoplication. Knatten CK, Fjeld JG, Medhus AW, Pripp AH, Fyhn TJ, Aabakken L, Kjosbakken H, Edwin B, Emblem R, Bjørnland K. J Pediatr Surg. 2017 Apr;52(4):540-543. doi: 10.1016/j.jpedsurg.2016.09.068. Epub 2016 Oct 14. PMID: 28277299
  12. Demonstration of Tissue Resident Memory CD8 T Cells in Insulitic Lesions in Adult Patients with Recent-Onset Type 1 Diabetes. Kuric E, Seiron P, Krogvold L, Edwin B, Buanes T, Hanssen KF, Skog O, Dahl-Jørgensen K, Korsgren O. Am J Pathol. 2017 Mar;187(3):581-588. doi: 10.1016/j.ajpath.2016.11.002. PMID: 28212742
  13. Laparoscopic surgery for pancreatic neoplasms: the European association for endoscopic surgery clinical consensus conference. Edwin B, Sahakyan MA, Abu Hilal M, Besselink MG, Braga M, Fabre JM, Fernández-Cruz L, Gayet B, Kim SC, Khatkov IE; EAES Consensus Conference Study Group. Surg Endosc. 2017 May;31(5):2023-2041. doi: 10.1007/s00464-017-5414-3. Epub 2017 Feb 15. PMID: 28205034
  14. Outcome after laparoscopic and open resections of posterosuperior segments of the liver. Scuderi V, Barkhatov L, Montalti R, Ratti F, Cipriani F, Pardo F, Tranchart H, Dagher I, Rotellar F, Abu Hilal M, Edwin B, Vivarelli M, Aldrighetti L, Troisi RI. Br J Surg. 2017 May;104(6):751-759. doi: 10.1002/bjs.10489. Epub 2017 Feb 13. PMID: 28194774
  15. Resection of synchronous liver metastases between radiotherapy and definitive surgery for locally advanced rectal cancer: short-term surgical outcomes, overall survival and recurrence-free survival. Labori KJ, Guren MG, Brudvik KW, Røsok BI, Waage A, Nesbakken A, Larsen S, Dueland S, Edwin B, Bjørnbeth BA. Colorectal Dis. 2017 Aug;19(8):731-738. doi: 10.1111/codi.13622. PMID: 28181384
  16. Laparoscopic Versus Open Liver Resection for Colorectal Metastases in Elderly and Octogenarian Patients: A Multicenter Propensity Score Based Analysis of Short- and Long-term Outcomes. Martínez-Cecilia D, Cipriani F, Vishal S, Ratti F, Tranchart H, Barkhatov L, Tomassini F, Montalti R, Halls M, Troisi RI, Dagher I, Aldrighetti L, Edwin B, Abu Hilal M. Ann Surg. 2017 Jun;265(6):1192-1200. doi: 10.1097/SLA.0000000000002147. PMID: 28151797
  17. Randomized clinical trial of open versus laparoscopic left lateral hepatic sectionectomy within an enhanced recovery after surgery programme (ORANGE II study).Wong-Lun-Hing EM, van Dam RM, van Breukelen GJ, Tanis PJ, Ratti F, van Hillegersberg R, Slooter GD, de Wilt JH, Liem MS, de Boer MT, Klaase JM, Neumann UP, Aldrighetti LA, Dejong CH; ORANGE II Collaborative Group.
  18. Br J Surg. 2017 Apr;104(5):525-535. doi: 10.1002/bjs.10438. Epub 2017 Jan 31. PMID: 28138958
  19. Navigating the mesentery: part II. Vascular abnormalities and a review of the literature. Nesgaard JM, Stimec BV, Bakka AO, Edwin B, Ignjatovic D; RCC study group. Colorectal Dis. 2017 Jul;19(7):656-666. doi: 10.1111/codi.13592. PMID: 28008705
  20. Perioperative outcomes and survival in elderly patients undergoing laparoscopic distal pancreatectomy. Sahakyan MA, Edwin B, Kazaryan AM, Barkhatov L, Buanes T, Ignjatovic D, Labori KJ, Røsok BI. J Hepatobiliary Pancreat Sci. 2017 Jan;24(1):42-48. doi: 10.1002/jhbp.409. PMID: 27794204
  21. Role of laparoscopic enucleation in the treatment of pancreatic lesions: case series and case-matched analysis. Sahakyan MA, Røsok BI, Kazaryan AM, Barkhatov L, Haugvik SP, Fretland ÅA, Ignjatovic D, Labori KJ, Edwin B. Surg Endosc. 2017 May;31(5):2310-2316. doi: 10.1007/s00464-016-5233-y. Epub 2016 Sep 12. PMID: 27620912 
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