Institute for Surgical Research

The institute is a contemporary experimental and molecular medicine research unit organized under Division of Cardiovascular and Pulmonary Diseases. We have strong research programs in cardiovascular, pulmonary, cancer, and stem cell research, as well as in tissue engineering and orthopedic research. The institute has a multidisciplinary staff of biochemists, molecular biologists, physiologists, physicists, and medical doctors.

Core Facility
The core facility for large animal research is a regional technological core facility supported by the South-Eastern Norway Regional Health Authority (Helse Sør-Øst RHF). The purpose of the core facility is to provide facilities (fully equi...
Molecular Cardiology
Heart failure, the clinical syndrome of end-stage cardiac disease of diverse etiologies, is a major cause of morbidity and mortality. In evolving heart failure, multiple compensatory actions are triggered in order to maintain cardiac output...
Integrated Cardiovascular Function
The group studies cardiac mechanics in experimental models and in patients. The general objective is to gain new insights into mechanisms of cardiovascular disease and to develop new imaging modalities which quantify disease processes and c...
Experimental Cell Transplantation
Type 1 diabetes (T1D) is an autoimmune disease caused by destruction of the alpha- and beta cells in the pancreas. In spite of optimal insulin therapy periods of hyperglycemia induce serious vascular- and neurological complications that nee...
ProCardio
Many heart diseases have a chronic course with expected worsening over time, such as valve diseases, heart failure, heart muscle diseases and heart damage after cancer treatment. It is important to find the right time to initiate a treatmen...
HTH Centre of Excellence
The goal of the cross-disciplinary international Hybrid Technology Hub - Centre for Organ on a Chip-Technology is to develop an open source “organ on a chip" platform that reproduces core functionalities of the human body and allows real ti...

Institute for Surgical Research

Core Facility

Molecular Cardiology

Integrated Cardiovascular Function

Experimental Cell Transplantation

ProCardio

HTH Centre of Excellence

News

Selection of an appropriate 3D context when studying stem cell models

Pancreas-on-a-Chip Technology for Transplantation Applications

A Worldwide Survey of Activities and Practices in Clinical Islet of Langerhans Transplantation

Exogenous high glucose levels impact different protein subsets in a concentration-dependent manner

Feasibility study of using high-throughput drug sensitivity testing

Neuroscience - from the clinic to the laboratory and back

A Small-Molecule Tankyrase Inhibitor Reduces Glioma Stem Cell Proliferation

Real-world validity of randomized controlled phase III trials

A promising pipeline of novel medicines

Abstracts during ESC 2022

Holographic Display for Quantification of Mitral Annular Dynamics

Estimating Regional Myocardial Contraction Using Miniature Transducers on the Epicardium

Automatic detection of valve events by epicardial accelerometer

An epicardially placed accelerometer can assess changes in preload in real-time.

Td as a potential biomarker

Multicentre study investigates determinants of LA reservoir and pump strain

Is it time to leave diagnostics based on ejection fraction?

ESC Cardio Talk featuring Professor Smiseth and Dr. Bøe

Non-invasive markers for the improvement of cardiac diagnostics

CRT Candidates - A Machine Learning Approach

Dissertation Jan Egil Brattgjerd

Dissertation Simen W. Schive

Exercise training improves cardiac function

Tribune Therapeutics

CCN2 protein, a novel finding

Dissertation Erlend Skaga

18th Annual CHFR Symposium on Heart Research

Dissertation John Moene Aalen