For application in clinical diagnostics, it is important to
understand which factors other than LV filling pressure determine the magnitude
of the LA strain components. Therefore, the present multicentre study
investigates determinants of LA reservoir and pump strain by studying patients
with a wide range of cardiac disorders. Furthermore, the study investigates how
LA strain may be used in combination with other echocardiographic parameters in
the evaluation of LV filling pressure. The study is done with echocardiographic
equipment from different vendors, and invasive pressure is used as gold
standard for LV filling pressure.
In patients with reduced LV systolic function, LA reservoir
and pump strain predicted LV filling pressure better than conventional
echocardiographic markers. High normal values of LA pump strain identified
normal filling pressure with high accuracy. When used in combination with the
conventional markers, LA strain increases the feasibility of using echo Doppler
parameters to estimate LV filling pressure as it provides an additional
variable to consider when one of the others is missing.
Left atrial (LA) reservoir and pump strain measured by speckle tracking echocardiography are proposed as supplementary markers of left ventricular filling pressure.
The proposed protocol including standardization of how to measure strain, and other echocardiographic and haemodynamic parameters was agreed on by all the participating centres. All statistical analyses were performed at the core laboratory at Oslo University Hospital.
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Determinants of left atrial reservoir and pump strain anduse of atrial strain for evaluation of left ventricular filling pressure
Eur Heart J Cardiovasc Imaging. 2021 Dec 18;23(1):61-70.
Katsuji Inoue, Faraz H Khan, Espen W Remme, Nobuyuki Ohte, Eusebio García-Izquierdo, Michael Chetrit, Vanessa Moñivas-Palomero, Susana Mingo-Santos, Øyvind S Andersen, Einar Gude, Arne K Andreassen, Tom Kai Ming Wang, Shohei Kikuchi, Marie Stugaard, Jong-Won Ha, Allan L Klein, Sherif F Nagueh, Otto A Smiseth
Shared under a Creative Commons license CC BY-NC (Creative Commons — Attribution-NonCommercial 4.0 International — CC BY-NC 4.0)