Novel imaging modalities for myocardial tissue characterisation
The research project focusses on novel imaging modalities for myocardial tissue characterisation by cardiac magnetic resonance imaging and high frame rate echocardiography. Remodelling of the myocardium and development of myocardial fibrosis is associated with cardiac dysfunction and severe arrhythmia. Enhanced imaging techniques for myocardial tissue characterisation may improve diagnostics and treatment across a broad spectrum of cardiac diseases.
The aims of the project are to fill existing research gaps regarding myocardial fibrosis in athletes and patients with cardiac diseases as well as to enhance non-invasive myocardial tissue characterisation by mechanical wave imaging using high frame rate echocardiography.
Publications
- No adverse association between exercise exposure and diffuse myocardial fibrosis in male endurance athletes (Link to publication).
Contributions
- Kristoffer Andresen, Lars Gunnar Klæboe, Øyvind Haugen Lie, Kaspar Broch, Anette Borger Kvaslerud, Gerhard Bosse, Einar Hopp, Kristina Hermann Haugaa, Thor Edvardsen (2021). Male elite endurance athletes have no signs of diffuse myocardial fibrosis by T1 mapping. Abstract at 19th annual Oslo Symposium on Heart Research hosted by ProCardio Center for Innovation and NORHEART Norwegian PhD School of heart research.
- Kristoffer Andresen, Lars Gunnar Klæboe, Øyvind Haugen Lie, Kaspar Broch, Anette Borger Kvaslerud, Gerhard Bosse, Einar Hopp, Kristina Hermann Haugaa, Thor Edvardsen (2021). “No signs of diffuse myocardial fibrosis by T1 mapping in male elite endurance athletes”. ePoster at EuroEcho 2021 online congress.
- Kristoffer Andresen (2024). “Mechanical Wave Imaging in Acute Coronary Syndrome.” Presentation at the Leuven Meeting on Myocardial Function Imaging 2024.
- Kristoffer Andresen, Torvald Espeland, Solveig Fadnes, Lasse Løvstakken, Helge Skulstad, Kristina Haugaa, Thor Edvardsen (2024). “Mechanical wave velocities by clutter filter wave imaging detects myocardial dysfunction in acute coronary syndrome.” Moderated poster session at ESC 2024.
Researchers involved
- Kristoffer Andresen, MD/PhD fellow, OUS
- Lisa-Marie Selmer, MD/PhD fellow, OUS
- Main supervisor: Thor Edvardsen, MD/Professor, OUS/UiO
- Sigrun Ådnegard Skarstad, MD/PhD fellow, OUS
- Marianne Forså, MD/PhD fellow, OUS
- Jorun Tangen, MD/PhD fellow, OUS
- Thuy Mi Tran Nguyen, MD/PhD fellow, OUS
- Bendik Skinningsrud, MD/PhD fellow, OUS
The project is performed in collaboration with GE HealthCare and NTNU.