Risk Stratification of Patients With Mitral Valve Prolapse by Precision Medicine
This research project focuses on the understanding of the pathogenesis of mitral valve prolapse and associated risk markers for ventricular arrythmia. We aim to increase knowledge about factors correlating with phenotypes of the disease.
Through this project, we aim to enhance our understanding of the pathogenesis of mitral valve prolapse, with the primary objective of developing improved tools for risk stratification for both patients and their family members. The effect of mitral surgery on the burden of ventricular arrythmia is not well known and will be further investigated through our project. As part of this project, we will investigate genetic variants possibly associated with the burden of ventricular arrhythmia and phenotype within the patient group, aiming to better understand their genetic underpinnings. This project is in collaboration with our partners at Oslo University Hospital and K.G. Jebsen Center for Genetic Epidemiology.
Researchers involved
- Julie Bergh, MD/PhD fellow, OUS
- Christian K. Five, MD/PhD fellow, OUS
- Project leader/Co-supervisor: Kristina Haugaa, MD/Professor, OUS/UiO
- Main supervisor: John-Peder Kvitting, MD/Associated Professor, OUS/UiO
Collaborators
HUNT Center for Molecular and Clinical Epidemiology (MCE)