Kontaktinformasjon
Gruppeleder Per Steinar Halvorsen
Telefon: 23 07 01 00/mobile 46 43 14 99
E-mail: sthalvor@ous-hf.no
Kontaktinformasjon til gruppens medlemmer finnes lengre ned på siden.
Besøksadresse/Postadresse:
The Intervention Centre, Division of Emergencies and Critical Care
OUH-Rikshospitalet
Postboks 4950, 0424 Oslo
Beskrivelse av forskningsprofil
Main aims:
Develop and test new technologies in cardiovascular monitoring
Cardiovascular response to new cardiovascular therapies
Myocardial function in therapeutic hypothermia and severe sepsis
This includes evaluating hemodynamic responses of
1) new cardiovascular image guided procedures,
2) ECMO strategies,
3) treatment for end stage heart failure with ventricular assist devices (VAD).
Langsiktig mål
To translate new concepts in technology and physiology into clinical practice.
Gruppens medlemmer
Hovedmedlemmer
Senior researchers
PhD-candidates
- Viesturs Kerans, MD, The Intervention Centre. viesturs.kerans@medisin.uio.no. HYPOTHERMIA
- Harald Bergan, MD, Dep. of Anesth. haaber@ous-hf.no. ECMO
- Ole-Johannes Grymyr, MD, The Intervention Centre. olegry@ous-hf.no. SENSORS
- Itai Schalit, The Intervention Centre, MD, itasch@ous-hf.no. LVAD/SENSORS
- Kristin Wisløff-Aase, MD, Dep.of Anesthesia. HYPOTHERMIA
- Siv Hestenes, MD, The Intervention Centre/Sykehuset Akser og Bærum.smereteh@online.no. SEPSIS
- Hilde Karlsen, MD, Dep.of Anesthesia. hikarl@ous-hf.no. ECMO
- Marte Sævik, MD, The Intervention Centre/Dep. Of Cardiology, masa2@ous-hf.no. TAVI
Assosierte medlemmer
Senior researchers
- Professor Erik Fosse, The Intervention Centre. erik.fosse@medisin.uio.no
- Professor Thor Edvardsen, Department of Cardiology. Thor.edvardsen@medisin.uio.no
- Professor Arnt Fiane, Department of Cardiothoracic Surgery, afiane@ous-hf.no.
- Ass. Professor Ole Jacob Elle, The Intervention Centre. oelle@ous-hf.no
- Professor Svend Aakhus, Department of Cardiology, saakhus@ous-hf.no
- Lars Aaberge, Department of Cardiology, laraab@ous-hf.no
- Jan Otto Beitnes, Department of Cardiology, jbeitnes@ous-hf.no
- Espen Remme, Department of Cardiology/The Intervention Centre. espere@ous-hf.no
PhD candidates:
Prosjekter
- TAVI: is myocardial reserve related to long term outcome?
- Accelerometer for detection of thromboembolic events in LVAD
- Accelerometer/gyro/magnetometer for monitoring changes in right and left ventricular load and detection of graded myocardial ischemia.
- Can betablockers improve survival and cardiovascular function after cardiac arrest: an experimental ECMO study
- Left and right ventricular dysfunction in severe sepsis; the effect of pulmonary hypertension and interventricular septal shift
- Myocardial effects of therapeutic hypothermia in cardiac surgery
- Effects of epinephrine and betablockers on systolic and diastolic left ventricular function during therapeutic hypothermia
- Multifunctional pacemaker systems for cardiac resynchronization therapy (CRT)
Samarbeid
- OSCAR research network at Oslo University Hospital: Professor K. Sunde
- WiBEC EU-project at The Intervention Centre: Professor Ilangko Balasingham,
- Biosensor Research Group at Oslo University Hospital: Professor T. I. Tønnessen
- Complement Research Group at Oslo University Hospital: Professor Tom Eirik Mollnes
- University College of Southeast Norway: Professor Kristin Imenes
Utvalgte publikasjoner
- Hyler S, Espinoza A, Skulstad H, Fosse E, Halvorsen PS. Left ventricular function can be continuously monitored with an epicardially attached accelerometer sensor. Eur J Cardiothorac Surg. 2014;(2): PMID:24482390
- Grymyr OH, Nguyen AT, Tjulkins F, Espinoza A, Remme EW, Skulstad H, Fosse E, Imenes K, Halvorsen PS. Continuous monitoring of cardiac function by 3-dimensional accelerometers in a closed-chest pig model. Interact Cardiovasc Thorac Surg. 2015; 21:573-82. doi: 10.1093/icvts/ivv191. PMID: 26254463
- Grymyr OJ, Beitnes JO, Eidet J,Tølløfsrud S, Fiane F, Skulstad H, Fosse E, Halvorsen PS. Detection of intraoperative myocardial dysfunction by accelerometer during aortic valve replacement. Interact CardioVasc Thorac Surg 2016; doi:10.1093/icvts/ivw326.
- Krogh MR, Nghiem GM, Halvorsen PS, Elle OJ, Grymyr OJ, Hoff L, Remme EW. Gravity Compensation
Method for Combined Accelerometer and Gyro Sensors Used in Cardiac
Motion Measurements. Ann Biomed Eng.
2017. doi: 10.1007/s10439-017-1798-4. PMID: 28116541
- Espinoza A,
Halvorsen PS,
Skulstad H, Lundblad R, Bugge JF, Hoff L, Fosse E, Edvardsen T.
Automated detection of myocardial ischaemia by epicardial miniature
ultrasound transducers-a novel tool for patient monitoring during
cardiac surgery. Eur J
Cardiothorac Surg. 2011
PMID:20627751
- Hyler S,
Pischke SE, Halvorsen PS,
Espinoza A, Bergsland J, Tønnessen TI, Fosse E, Skulstad H.
Continuous monitoring of regional function by a miniaturized
ultrasound transducer allows early quantification of low-grade
myocardial ischemia. J Am Soc
Echocardiogr. 2015;28:486-94.
PMID:25636368
- Eidet J, Dahle G, Bugge JF,
Bendz B, Rein KA, Aaberge L, Offstad JT, Fosse E, Aakhus S,
Halvorsen PS. Long-term
outcomes after transcatheter aortic valve implantation: the impact
of intraoperative tissue Doppler echocardiography. Interact
Cardiovasc Thorac Surg. 2016;23(3):403-9. doi:
10.1093/icvts/ivw159. PMID: 27241050
- Bergan HA, Halvorsen
PS, Skulstad H, Fosse E, Bugge JF. Does
therapeutic hypothermia during extracorporeal cardiopulmonary
resuscitation preserve cardiac function? J
Transl Med. 2016 Dec 20;14:345.
doi: 10.1186/s12967-016-1099-y
- Espinoza A,
Kerans V, Opdahl A, Skulstad H, Halvorsen
PS, Bugge JF, Fosse E,
Edvardsen T. Effects of therapeutic hypothermia on left ventricular
function assessed by ultrasound imaging. J
Am Soc Echocardiogr.
2013;26(11). PMID:23891124
- Hestenes SM,
Halvorsen PS,
Skulstad H, Remme EW, Espinoza A, Hyler S, Bugge JF, Fosse E,
Nielsen EW, Edvardsen T. Myocardial function in therapeutic
hypothermia and severe sepsis. Advantages of strain echocardiography
in assessment of myocardial function in severe sepsis: an
experimental study. Crit Care
Med. 2014: PMID:24633187